Prolonged and regular use of alcohol leads to many health problems such as:
• Handicapped mental functioning – slower reaction times and loss of verbal memory are associated with drinking and mild neurological impairments such as insomnia and headaches.
• Liver disorders – about 10% to 35% of heavy drinkers develop alcoholic hepatitis (damaging inflammation in the liver). Between 10% to 20% of these ones develop cirrhosis, a progressive scarring of the liver that can ultimately be fatal.
• Gastrointestinal problems – Violent vomiting can produce tears in the junction between the stomach and gullet. Alcoholism hs a high risk for hemorrhoids,  diarrhea and increases the risk for gastric ulcer.
• Heart disease – heavy drinking is associated with abnormal blood clotting factors, high blood pressure, increased risk for stroke, irregular heart beats and an enlarged heart.
• Lung failure  – heavy alcoholism is often associated with a very serious pneumonia and has also been shown as a contributing factor in acute respiratory distress syndrome, a type of potentially fatal lung failure 
• Risk of cancer – alcoholics have a.  rate of neoplasm 10 times higher than nonalcoholics. prolonged heavy drinking has been implicated in upper digestive system and upper airway cancers, esophageal cancer,  breast cancer, cervical and vaginal cancers. Alcohol is not usually the direct cause but evidences suggest that it increases other risk factors.
• Skin, muscle and bone disorders – heavy alcoholism is also associated with osteoporosis (loss of bone density), muscular deterioration, skin sores, and itching.
• Pregnancy and infant development complications – even moderate amounts of alcohol can have damaging effects on the developing of foetus, including low birth weight and an increased risk for miscarriage. High amounts can cause foetal alcohol syndrome, a condition that can cause mental and growth retardation.
• Enlarged risk for other addictions – researchers have found common genetic links between alcoholics and smokers addicted to nicotine.
• Death from many sources, primarily alcohol toxemia.
• Pancreatitis or inflammation of the pancreas (both the acute and chronic form).
• Polyneuropathy, or damage to the nerves leading to poor sensation of pain and impaired mobility.
• Depression, insomnia, anxiety and suicide.
• Nutritional deficiency of folic acid, thiamine (vitamin B1) and several others.
• Wernicke-Korsakoff syndrome, a neuropsychiatric disorder caused by thiamine deficiency that results from poor nutrition in some alcoholics.
• Sexual dysfunction.